Fig. 2: Schematic representation of PCK1 involved in glucose and lipid metabolism. Please see the text for specific details.

arrows indicate positive effects. perpendicular bars indicate negative effects. (AC-coa, Acetyl-CoA; P; phosphate, S, Serine; GA3p, glyceraldehyde-3-phosphate; 3PG, 3-Phosphoglycerate; 2PG, 2-Phosphoglycerate;OAA, Oxaloacetete; PPP, Pentose phosphate pathway, PPP; HBP, Hexosamine biosynthesis pathway;G6PD,Glucose-6-phosphate dehydrogenase; 6PGD, 6-phosphogluconate dehydrogenase; TKT, Transketolase, UDP-GlcNAc, Uridine diphosphate-N-acetylglucosamine).