Fig. 6: E2 inhibited ferroptotic stress and M1 transition of BV2 cells via ATF4. | Cell Death Discovery

Fig. 6: E2 inhibited ferroptotic stress and M1 transition of BV2 cells via ATF4.

From: 17β-estradiol alleviated ferroptotic neuroinflammation by suppressing ATF4 in mouse model of Parkinson’s disease

Fig. 6

A Cell viability results of BV2 cells treated with different conditions. B Influence of E2 on expressions of M2- and M1-related markers in BV2 cells. C E2 reduced L-ROS levels in BV2 cells treated with MPP+. D, E Level of MDA and GSH in BV2 cells. F L-ROS levels in BV2 cells. G The live/dead assay of BV2 cells (the green fluorescence stands for living cells and the red fluorescence represents dead cells). H TEM images of the ultrastructure in BV2 cells from each treatment group. *P < 0.05, **P < 0.01.

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