Fig. 7: E2 ameliorated biological behavior.

A Schematic representation of the experimental timeline. B Representative movement trajectories of mice in the open field test under different treatment conditions: Control (Con), E2, MPTP, and MPTP + E2. C Center frequency, (D) Central distance traveled (cm), (E) Total distance traveled (cm), and (F) Average speed (cm/s) of mice in each group. G, H Behavioral changes were assessed using pole test. I Behavioral changes were tested using wire hang test. *P < 0.05, **P < 0.01.