Fig. 3: The molecular mechanisms of PM2.5-regulated ferroptosis.
From: Ferroptosis induced by environmental pollutants and its health implications
PM2.5 exposure promotes ferroptosis by regulating ferritinophagy, NRF2, CYP1B1, AMPK, and SIRT3, whereas tectoridin, astragaloside IV, melatonin, rosavin, and sipeimine can prevent PM2.5-induced ferroptosis in an NRF2-dependent manner. This figure was created using BioRender (https://biorender.com/).
