Fig. 4: Differences between the two groups SREBF1_POS and SREBF1_NEG.
From: SREBF1-based metabolic reprogramming in prostate cancer promotes tumor ferroptosis resistance
A Volcano plot showing the differential gene expression analysis between SREBF1_POS and SREBF1_NEG groups. B Gene Set Variation Analysis (GSVA) comparing the SREBF1_POS and SREBF1_NEG groups. The gene set used is CP:WIKIPATHWAYS from MSigDB. C Violin plot displaying the expression levels of selected genes between SREBF1_POS and SREBF1_NEG groups. D Pathway map of ferroptosis and lipid metabolism. E Schematic diagram of cholesterol synthesis, from acetyl-CoA to cholesterol. F Dot plot showing the expression levels of cholesterol synthesis-related genes between SREBF1_POS and SREBF1_NEG groups.
