Fig. 7: Analysis of neurite length in eDRGs and adult DRGs.

eDRGs explants and adult DRGs neurons were treated with hdASC conditioned media derived from 7 different patients [C, eDRGs (scale bar = 200 µm) and F adult DRGs (scale bar = 100 µm)]. The width of the neurite crown and the neurite length were measured respectively in eDRG explants and in adult DRG neurons. A, D graphs showed the percentage of a determined measurement of the width of the neurite crown and the neurite length. ANOVA analysis with Bartlett’s test showed a significant increase of the neurite length after conditioned media obtained from hdASC maintained in the presence of the agonist APE both in eDRGs and adult DRGs (B, ***P < 0.001; E, *P < 0.05).