Fig. 9: PGK1 and PCMT1 knockdown modulates PI3K/AKT/mTORC pathway activity in BC cell lines (MDA-MB-231 and MCF7). | Cell Death Discovery

Fig. 9: PGK1 and PCMT1 knockdown modulates PI3K/AKT/mTORC pathway activity in BC cell lines (MDA-MB-231 and MCF7).

From: Development of a breast cancer invasion score to predict tumor aggressiveness and prognosis via PI3K/AKT/mTOR pathway analysis

Fig. 9

Relative mRNA expression levels of key genes involved in the PI3K/AKT/mTORC signaling pathway with PGK1 (A) and PCMT1 (B) knockdown in MDA-MB-231 cells. Relative mRNA expression levels of the same set of genes with PGK1 (C) and PCMT1 (D) knockdown in MCF7 cells. Statistical significance: *P < 0.05, **P < 0.01, ***P < 0.001, ns: not significant.

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