Fig. 7: Skp2 is overexpressed and positively correlated with Survivin and p-Akt in OSCC tissues. | Cell Death Discovery

Fig. 7: Skp2 is overexpressed and positively correlated with Survivin and p-Akt in OSCC tissues.

From: E3 ligase Skp2-mediated stabilization of survivin contributes to radioresistance

Fig. 7

A Representative IHC staining images of tumor tissues from OSCC patients with high levels of Skp2, p-Akt Survivin protein or low levels of Skp2, p-Akt Survivin protein. Scale bar, 20 μm. B, C Percentage of samples with high or low Skp2 expression compared with p-Akt (B) and Survivin (C) expression levels. D Percentage of samples with high or low p-Akt expression compared to the expression levels of Survivin. E–G Scatter plots showing the positive correlation between p-Akt and Skp2 (E), Survivin and Skp2 (F), and Survivin and p-Akt (G) expression in OSCC tumor tissues, respectively.

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