Fig. 2: C12ORF49 knocking-down inhibited the growth of HCC cells. | Cell Death Discovery

Fig. 2: C12ORF49 knocking-down inhibited the growth of HCC cells.

From: C12ORF49 inhibits ferroptosis in hepatocellular carcinoma cells via reprogramming SREBP1/SCD1-mediated lipid metabolism

Fig. 2

The effectiveness of C12ORF49 knockdown in HLF and HLE cells was validated by qRT-PCR (A) and WB (B) experiments. C, D The impact of C12ORF49 knockdown on proliferation capabilities of HLF and HLE cells were assessed by MTS and colony assays. E, F C12ORF49 knockdown on cell cycle distribution was assessed via flow cytometry and EdU incorporation assays (Scale bar = 20 µm). G Cell apoptosis was analyzed upon C12ORF49 knockdown. Values are expressed as mean ± SEM from three individual experiments (n = 3).

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