Fig. 2: IDO1 expression is negatively associated with BC prognosis. | Cell Death Discovery

Fig. 2: IDO1 expression is negatively associated with BC prognosis.

From: Heightened IDO1 levels predict Bacillus Calmette-Guèrin failure in high-risk non-muscle-invasive bladder cancer patients

Fig. 2

A IDO1 log2 expression in tumor (black box plot frame) versus normal (green box plot frame) samples retrieved from TCGA. Bladder cancer (BC) is shown in bold. B IDO1 log2 expression in BC (red box plot) (n = 404) and normal tissue (grey box plot) (n = 28) retrieved from GEPIA. C Percentage of IDO1 mutations for each tumor type sample as in (A). (D-F) RNA-seq expression data of IDO1 in normal bladder tissue and in different BC molecular subtypes (D), stages (E) and weight status (F) retrieved from the TCGA database and analyzed by UALCAN. (G) Kaplan Meier disease free survival curves of BC patients (GSE32548, GSE48075, GSE31684) stratified by high (n = 180) or low (n = 117) IDO1 expression levels. Statistical analysis has been performed with log-rank test.

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