Fig. 3: Targeting Kv1.3 channel inhibits polarizing M1 macrophages in UUO mice.

A Respective FCM analysis the percentage of monocytes in peripheral blood of experimental mice. B Respective FCM analysis of M1 (CD11b+CD86+) and M2 (CD11b+CD206+) macrophages changes in experimental mice. C Analysis of the proportion of monocytes in peripheral blood and the proportion of M1 (CD11b+CD86+) and M2 (CD11b+CD206+) macrophages changes in renal tissue. D Representative images of CD86 and CD206 as detected by immunohistochemical staining.