Fig. 2: METTL13 knockdown inhibited the survival and growth of human AML cells.
From: METTL13 is essential for the survival of acute myeloid leukemia cells by regulating MYC
A and B Validation of the knockdown effect of METTL13 using RT-qPCR and Western blot in HL-60 and K562 cells. C Representative growth images of HL-60 and K562 cells on day 4 after METTL13 knockdown. D Proliferation trend of HL-60 and K562 cells by cell counting after METTL13 knockdown. E and F Cell cycle distribution of HL-60 and K562 cells conducted by flow cytometry on day 4 after METTL13 knockdown. G and H Percentages of apoptotic HL-60 and K562 cells were conducted by flow cytometry on day 4 after METTL13 knockdown. I and J Expression analysis of CD11b in HL-60 cells on day 4 after METTL13 knockdown. Data were presented as mean ± SD (Student’s test, *p < 0.05, **p < 0.01, ***p < 0.001).
