Fig. 4: Exploring potential targeted genes of tRF-29-79MP9P9NH525 (tRF-29). | Cell Death Discovery

Fig. 4: Exploring potential targeted genes of tRF-29-79MP9P9NH525 (tRF-29).

From: Identification of tRF-29-79MP9P9NH525 as a biomarker and tumor suppressor of gastric cancer via regulating KIF14/AKT pathway

Fig. 4

A, B qRT-PCR results of nucleoplasmic separation (A) and FISH assay (B) identified the distribution of tRF-29 in gastric cancer cells. C, D The heatmap (C) and volcano plots (D) of the RNA sequence results in AGS cells treated by tRF-29 mimics. E The overlapped genes that were predicted by Miranda & TargetScan, and the downregualted genes in AGS cells treated by tRF-29 mimics. F The bubble diagram exhibited the biological process classification of tRF-29’s targeted genes. G The expression level of aquaporin 11 (AQP11), kinesin family member 14 (KIF14), sphingosine-1-phosphate receptor 3 (S1PR3), and thrombospondin 1 (THBS1) were detected in gastric cancer cells with tRF-29 upregulation or downregulation. n = 3; *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, ns no significance.

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