Fig. 7: Reduced KIF14 expression reversed the effects of tRF-29-79MP9P9NH525 (tRF-29) on the proliferation of gastric cancer. | Cell Death Discovery

Fig. 7: Reduced KIF14 expression reversed the effects of tRF-29-79MP9P9NH525 (tRF-29) on the proliferation of gastric cancer.

From: Identification of tRF-29-79MP9P9NH525 as a biomarker and tumor suppressor of gastric cancer via regulating KIF14/AKT pathway

Fig. 7

A The downregulated effect of si-KIF14 was determined by qRT-PCR. n = 3. B EdU assay revealed the rescue effects of KIF14 knockdown in cells treated by tRF-29 inhibitor. n = 3. C Reduced KIF14 expression trapped more cells in G0/G1, which was reduced by tRF-29 inhibitor. n = 3. D The activated p-AKT(S473) pathway by tRF-29 inhibitor was restrained by KIF14 downregulation. n = 3. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001; ns no significance.

Back to article page