Fig. 8: Cellular constitution and cell death-related genes on immune cells in TNBC. | Cell Death Discovery

Fig. 8: Cellular constitution and cell death-related genes on immune cells in TNBC.

From: Mitochondrial reactive oxygen species promote cancer metastasis and tumor microenvironment immunosuppression through gasdermin D

Fig. 8

a UMAP plot illustrating all CD45+ cells in TNBC mouse models from GEO dataset. The 22 cell populations identified via transcriptional profiles indicated by different colors. b The heat map showing relative gene expression profile of genes in the top2 per cell in each cluster. c, e Violin plots showing the expression of Casp1, Casp4, Casp9, Bcl2, Cycs, Gls and Pdha1 based on cluster ID. d, g Feature plots displaying expression profile of genes mentioned in the above 22 clusters. f Dotplot showing the average expression and expressed percentage of Bcl2, Cycs and Ctsc in 0–21 clusters.

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