Fig. 5: RGS3 knockdown reduces metastasis potential in vivo. | Cell Death Discovery

Fig. 5: RGS3 knockdown reduces metastasis potential in vivo.

From: RGS3 acts as a tumor promoter by facilitating the regulation of the TGF-β signaling pathway and promoting EMT in ovarian cancer

Fig. 5

A, B Tumor morphology and weight assessment 7 weeks after intraperitoneal injection of shRGS3 and control OVCAR8 cells. C The expression of RGS3, CD31, vimentin, and N-Cadherin was measured in IOD. D IHC analysis of RGS3, CD31, vimentin, and N-Cadherin expression in RGS3-knockdown tumors. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, (scale bars: 200 μm, 100 μm).

Back to article page