Fig. 1: LMNB2 is significantly elevated in HCC, negatively related to immune infiltration.
From: LMNB2-mediated high PD-L1 transcription triggers the immune escape of hepatocellular carcinoma
A Intersection of upregulated DEGs in drug-resistant HCC samples (GSE211850, GSE182593, GSE151412, and GSE192771). B Annotation and clustering for ST profiling. C Analysis expression of LMNB2 in HCC cells between patient responders and patient non-responders. D–F Debatching effect, clustering, and annotation for sc-RNA seq of 10 HCC samples (T) and 10 normal liver samples (P) (GSE235057). G Expression of LMNB2 in hepatocyte cells in sc-RNA seq of total10 HCC samples. H Expression of LMNB2 in hepatocyte cells in sc-RNA seq of separate 10 HCC samples. I Proportion of cell types in scRNA-seq of 10 HCC samples. J Proportion of CD4+ T cells in the 10 HCC samples grouped with high/low LMNB2 expression of hepatocyte cells. K Proportion of CD8+ T cells in the 10 HCC samples grouped with high/low LMNB2 expression of hepatocyte cells. L Proportion of NKT cells in the 10 HCC samples grouped with high/low LMNB2 expression of hepatocyte cells. M Proportion of B cells in the 10 HCC samples grouped with high/low LMNB2 expression of hepatocyte cells. Data are shown as mean ± SD (n ≥ 3). *p < 0.05, ns p ≥ 0.05.
