Fig. 3: Knockdown of FOXA1 decreased the chemosensitivity of NPC cells to cisplatin in vitro. | Cell Death Discovery

Fig. 3: Knockdown of FOXA1 decreased the chemosensitivity of NPC cells to cisplatin in vitro.

From: Targeting the FOXA1/BMI1 axis to overcome chemoresistance and suppress tumor progression in nasopharyngeal carcinoma

Fig. 3

A FOXA1-silenced CNE1 and CNE2 cells were subjected to a series of cisplatin concentrations to ascertain the IC50 values via the CCK-8 assay. Following treatment with cisplatin at 0.5 μg/mL for 48 h, these cells were assessed using: B the CCK-8 assay, C wound healing assays, (E, F) Transwell migration and invasion assays, and (G, H) flow cytometry. Data are presented as the mean ± SD from three replicates. NS, not significant; *P < 0.05, **P < 0.01 and #P < 0.001, as determined by one-way ANOVA test.

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