Fig. 2: EIF4EBP1 mRNA expression correlates with overall survival in all MB patients and in Group 3/Group 4 MB patients.

A–F Kaplan–Meier survival estimates of overall survival of MB patients stratified by their EIF4EBP1 mRNA expression levels across all MB patients (A, B), in Group 3 and 4 MB patients combined (C, D), in Group 3 MB patients (E) or in WNT MB patients (F) using data sets from the Cavalli et al. [8] and Pomeroy [40] cohorts as indicated. The data were obtained from R2 Genomics and visualization platform and the first versus last quartile was used as cut-off. Significance was calculated with the log-rank test.