Fig. 1: Comparison of SHMT2 expression in lung adenocarcinoma (LUAD) versus normal lung tissues.
From: RNA-mediated inhibition of mitochondrial SHMT2 impairs cancer cell proliferation

Boxplots display SHMT2 mRNA expression levels measured in TCGA samples: LUAD (n = 540, red) and normal (n = 59, blue). The yellow line within each box indicates the median; box limits represent the 25th and 75th percentiles; whiskers extend to 1.5× the interquartile range; open circles denote outliers. A two-tailed Student’s t-test indicates a highly significant increase in SHMT2 expression in LUAD compared to normal tissues (p = 6.5 × 10−84).