Fig. 5: Time-dependent receiver operating characteristic (ROC) curves and areas under the curve (AUCs) in the training, internal, and independent validation cohorts. | Cell Death Discovery

Fig. 5: Time-dependent receiver operating characteristic (ROC) curves and areas under the curve (AUCs) in the training, internal, and independent validation cohorts.

From: A long noncoding RNA-based serum signature predicts ado-trastuzumab emtansine (T-DM1) treatment benefit in HER2+ metastatic breast cancer patients: a multicenter cohort study

Fig. 5

A, B The time-dependent area under the ROC curve (AUC) at 1 and 2 years was used to assess the prognostic accuracy of the 4-lncRNA signature. C Comparison of the prognostic accuracy of the 4-lncRNA signature (high vs. low score) for T-DM1 response in patients with different clinicopathological characteristics. p values represent the AUC of the 4-lncRNA signature vs. the AUC of the clinical features. The AUC and 95% CI were calculated via the bootstrap method. The p values were two-sided on the basis of the bootstrap test.

Back to article page