Fig. 2: Transcriptional sequence analysis of MDA-MB-468 cells co-cultured with or without hADSC cells. | Cell Death Discovery

Fig. 2: Transcriptional sequence analysis of MDA-MB-468 cells co-cultured with or without hADSC cells.

From: Adipocyte-derived IL6 and triple-negative breast cancer cell-derived CXCL1 co-activate STAT3/NF-κB pathway to mediate the crosstalk between adipocytes and triple-negative breast cancer cells

Fig. 2

MDA-MB-468 of TNBC cells were co-cultured with hADSC cells or cultured separately. After 3 days, the cells were collected for transcriptional sequencing. A Differential gene volcano plot, red indicates differentially expressed upregulated genes, green represents differentially downregulated genes; B Differential gene heat map, red indicates differentially expressed upregulated genes, blue represents differentially downregulated genes. N = 3 co-expressed MDA-MB-468 cells and n = 3 single cultured MDA-MB-468 cells; C, D GO terms bio-enrichment analysis and KEGG pathway analysis of differentially expressed genes. C GO terminology biological enrichment analysis; D Bubble diagram of KEGG; E–N Enrichment analysis of GSEA pathway of differentially expressed genes.

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