Fig. 3: Impact of PARPi treatment on cell cycle regulation of ovarian cancer cells. | Cell Death Discovery

Fig. 3: Impact of PARPi treatment on cell cycle regulation of ovarian cancer cells.

From: Increased efficacy of PARP inhibitors against cisplatin-sensitive and -resistant ovarian cancer cells mediated via ATR and ATM inhibition

Fig. 3

A–G Cell cycle analysis of the indicated cell lines with either niraparib at 1 µM or 10 µM, or olaparib at 1 µM or 10 µM. Mean ± SD (n = 3) for the respective phase of the cell cycle. For statistical analysis, One-way ANOVA following Dunnett’s test was performed for each phase and cell line, *P < 0.05, **P < 0.01; ***P < 0.001; ****P < 0.0001.

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