Fig. 2: Identification of phenotypically distinct clusters in myeloid cell compartment in the mouse lungs. | Cell Death Discovery

Fig. 2: Identification of phenotypically distinct clusters in myeloid cell compartment in the mouse lungs.

From: IL-21-dependent Ly6C+Ly6G+CD4+ T cells found in lung enhance macrophages function against Actinobacillus pleuropneumoniae infection in mice

Fig. 2

A–C Analysis of the whole immune system across all the mouse lung tissues using mass cytometry (N = 17 samples, including 1,096,882 cells). A H-SNE represents the overall composition of the lung immune system. Expression profile of the indicated markers. B Density characteristics of the embedded cells. C A H-SNE plot shows the cluster partitions of major immune cell lineages in the lung. D A phenotypic heatmap (scale from blue to red) shows the median marker expression values and hierarchical clustering of each cell cluster in Fig. S2. E–W The bar plots show the proportion of the indicated cell clusters identified in panel D in each group. AM alveolar macrophages. *p < 0.05; **p < 0.01, using Mann-Whitney U test. Error bars show means ± SEM.

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