Fig. 4: Identification of CD4+ T cell clusters in WT and IL-21R−/− mice lungs infected with APP. | Cell Death Discovery

Fig. 4: Identification of CD4+ T cell clusters in WT and IL-21R−/− mice lungs infected with APP.

From: IL-21-dependent Ly6C+Ly6G+CD4+ T cells found in lung enhance macrophages function against Actinobacillus pleuropneumoniae infection in mice

Fig. 4

A A H-SNE embedding of 91,586 CD4+ T cells. Colors show the expression of the indicated markers. B A density map of CD4+ T cell compartment (left panel) and cluster partitions in different colors. (Right panel). C t-SNE plots showing the cell distribution in each indicated group (D) Phenotypic heatmap (scale from blue to red) shows the median marker expression values and hierarchical clustering of each cell cluster in CD4+ T cells. E–M Statistical analysis of the proportion of indicated clusters in CD4+ T cells in (D).*p < 0.05, using Mann-Whitney U test. Error bars show means ± SEM.

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