Fig. 3: Gas41 knockdown reduces H2A.Z occupancy globally.
From: Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity
a Venn diagram showing the overlap of Flag-GAS41 and H2A.Z occupied peaks. b Heatmap profiles of Flag-GAS41 and H2A.Z in control (shNT), Gas41 KD (shGas41) mESCs, and difference (Δ, shGas41-shNT). Gray indicates a reduction in Gas41 KD cells compared to the control cells. c Heatmaps profiles of Flag-GAS41 and H2A.Z occupancies at transcription start sites (TSSs) in cells as in b. The H3K4me3 profile in control cells are shown to define active promoters. d Heatmaps profiles of Flag-GAS41 and H2A.Z occupancies at enhancers in cells as in b. H3K4me1 ChIP-seq reads from GSM845238 is shown to define enhancers. e Genome browser views of the Flag-GAS41 (dark red) and H2A.Z (blue) ChIP-seq peaks on the indicated genes in cells as in c
