Fig. 8: Models of the regulation of tSG assembly by eIF4GI-G3BP interaction.
From: SG formation relies on eIF4GI-G3BP interaction which is targeted by picornavirus stress antagonists
a In normal condition, stresses promote the interaction between eIF4GI and G3BP, which leads to the assembly of eIF4GI into tSGs and the rescue of tSG formation. b-c The expression of G3BP-ΔRBD (b) or 2A/L (c) interferes eIF4GI-G3BP interaction to block tSG assembly
