Fig. 4: The interface of AFF4-THD dimer.

a Overview of interface of AFF4-THD dimer. Two molecules of the dimer are colored in cyan and slate, respectively. b, c Details of Core2 and Core1. Cartoon and surface representation are shown while the key residues are shown in stick model. The residues labeled with “’” represent that these residues are from the second molecule. The labels of F1014 and Y1096 are colored in red. In the surface model, F1014 and Y1096 are shown in hydrophobic pockets.