Fig. 1: LIR motif-dependent ATG8 interactions. | Cell Discovery

Fig. 1: LIR motif-dependent ATG8 interactions.

From: Activation and targeting of ATG8 protein lipidation

Fig. 1

During the process of macroautophagy, ATG8 family proteins participate in autophagosome formation at different stages from initiation to the fusion with the lytic compartment. These interactions are typically mediated by LIR motifs in the target proteins. In the scheme, the ATG8 interactors found in yeast and humans are shown. The ATG8 protein family members are depicted in green.

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