Fig. 4: ATG8 conjugation to single membranes in non-autophagic events.

Cartoon summarizing the recruitment of the ATG16L1 protein in ATG8 conjugation events that are not directly related to autophagy. The arrows indicate the recruitment of the ATG12–ATG5–ATG16L1 complex to single membranes. The factors recruiting the complex via the WD40 domain in ATG16L1 are highlighted in red.