Fig. 1: Flowchart for the development of the medium recipe used for pancreatic islet expansion.
From: In vitro expansion of pancreatic islet clusters facilitated by hormones and chemicals
The chemicals and hormones used in previous studies for stem cell expansion, differentiation and pancreatic islet cell conversion (upper panel) are classified by their reported function related to cell division and proliferation, islet identity, and cell renewal and regeneration (middle panel). The common factors are summarised and combined for the formulation of the medium recipe used for in vitro pancreatic islet cluster expansion.
