Fig. 5: qRT-PCR analysis of gene expression in expanded clusters compared to primary islets.
From: In vitro expansion of pancreatic islet clusters facilitated by hormones and chemicals
a Comparison of the expression of proliferation and cell cycle markers in pregnant mouse-expanded clusters vs isolated primary islets. b Comparison of the expression of pluripotency and regeneration markers in pregnant mouse-expanded clusters vs isolated primary islets. c Comparison of the expression of islet and pancreatic progenitor markers in pregnant mouse-expanded clusters vs isolated primary islets. d Comparison of the expression of proliferation and cell cycle markers in rat-expanded clusters vs isolated primary islets. e Comparison of the expression of pluripotency and regeneration markers in rat-expanded clusters vs isolated primary islets. f Comparison of the expression of islet and pancreatic progenitor markers in rat-expanded clusters vs isolated primary islets. *P < 0.05; **P < 0.01; ***P < 0.001; clusters were compared with primary islets. The data are shown as the mean ± SEM of at least three independent experiments. Data were analysed using unpaired two-tailed Student’s t-test.
