Fig. 3: Identified conopeptide transcripts and post-transcriptional peptides. | Cell Discovery

Fig. 3: Identified conopeptide transcripts and post-transcriptional peptides.

From: The first Conus genome assembly reveals a primary genetic central dogma of conopeptides in C. betulinus

Fig. 3

a Phylogeny of previously deduced conopeptide precursors with full-length signal peptides4. b−e Central dogma of the representative conopeptide CONOT103(Bt176). Regions in purple, green, and red represent the 1st, 2nd, and 3rd exons, or the corresponding sequences, respectively. Sequences highlighted in blue, orange, and red are signal peptides, pro-/post-peptides, and mature peptides of the precursor, respectively. f Functional conopeptides with post-translational modifications and/or N- and C-terminal truncations7 that were detected by MS. Amino acid sequences with open star illustrate amino acid modifications at hydroxy-prolines (P).

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