Fig. 3: The strong correlations suggest that the top 25 mutations form eight potential co-mutation patterns.
From: Potential transmission chains of variant B.1.1.7 and co-mutations of SARS-CoV-2
a The correlation heatmap of the top 25 mutations. These mutations could be grouped into several clusters with high Pearson-correlation-coefficient (PCC). b Regression analysis of mutations shows that eight clusters all denote the statistical significance level: ***P-value < E-44. c–f, g–i, j–k, and l–n show the transitions of the high-frequency mutations. The sky-blue represents the rate per day of initial residue in population and the golden represents the rate per day of substitution/mutant. These mutation transitions provide further evidence that the above mutations potentially form co-mutation patterns.
