Fig. 6: Cell–cell interaction networks in primary tumors and liver metastases of CRC. | Cell Discovery

Fig. 6: Cell–cell interaction networks in primary tumors and liver metastases of CRC.

From: A single-cell atlas of liver metastases of colorectal cancer reveals reprogramming of the tumor microenvironment in response to preoperative chemotherapy

Fig. 6

a Dot plot depicting the selected LR interactions enriched in treatment-naïve (left) and PC-treated (right) primary CRC tumors. Color intensity corresponds to the mean of average expression; dot size indicates the P values. Scales are shown on the right. b Dot plot depicting the selected LR interactions enriched in treatment-naïve tumors (left) and tumors treated with PC (right) in liver metastases. Two colors (red and black) are used to distinguish the cellular origin of each ligand/receptor.

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