Fig. 7

Diagram illustrating the reprogramming of TME in response to PC. The reprogramming of TME in response to PC. Top, schematic diagram of the reprogramming of TME in treatment-naïve (left) and treated (right) tumor in the primary CRC. Bottom, schematic diagram of the reprogramming of TME in treatment-naïve (left) and treated (right) tumor in liver metastases.