Fig. 7: Antisera induced by the yeast-derived monomeric and dimeric RBD vaccines efficiently neutralized SARS-CoV-2 variants. | Cell Discovery

Fig. 7: Antisera induced by the yeast-derived monomeric and dimeric RBD vaccines efficiently neutralized SARS-CoV-2 variants.

From: Yeast-produced RBD-based recombinant protein vaccines elicit broadly neutralizing antibodies and durable protective immunity against SARS-CoV-2 infection

Fig. 7

Neutralizing titers of week-6 anti-RBD-monomer (a) and anti-RBD-dimer sera (b) against B.1.1.7 and B.1.351 variants were measured using pseudovirus neutralization assay. For comparison, NT50s of antisera against WT pseudovirus (Fig. 6c) were also shown. Geometric means were calculated for each data set and shown. Each symbol represents one mouse. Statistical significance was determined by Student’s t-test and indicated as follows: ns, not significant.

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