Fig. 4: Deferentially expressed immune-related genes of CD8+ subset from top 20 TCR clonotypes paired scRNA-seq data.
From: Dynamics of TCR repertoire and T cell function in COVID-19 convalescent individuals
The volcano plot of significantly changed genes and the heatmap of selected granzyme- and interferon-related genes of CD3E+CD8A+CD4− clusters in top 20 TCR clonotypes from Discharged group vs. HD group (n = 6 per group) (a), from Follow-up group vs. HD group (n = 7 in Follow-up group, n = 6 in HD group) (b), and from Discharged group vs. Follow-up group (c). d The bubble plot of selected granzyme- and interferon-related genes’ expression level in Discharged, Follow-up, and HD groups (n = 6 in Discharged and HD group, n = 7 in Follow-up group) of CD3E+CD8A+CD4− clusters in top 20 TCR clonotypes. DC, Discharged group; FU, Follow-up group; HD, Healthy Donor group.
