Fig. 1: Cryo-EM structure of the hPol I ECpost.
From: Structure of the human RNA polymerase I elongation complex
a Schematic model of the DNA–RNA scaffold used in ECpost. RNA is numbered relative to the NTP addition site in the elongation complex. The template DNA is shown in blue, the nontemplate DNA in yellow, and RNA in cyan. The bases that built in our model are shown with color-filled circles. Residues involved in contacting nucleotides are indicated. b, c Cryo-EM map (b) and structural model (c) of the hPol I ECpost in two different views. Color scheme is indicated and used in all the figures below.
