Fig. 5: Disease-associated mutations in hPol I.
From: Structure of the human RNA polymerase I elongation complex
a Overall structure of the hPol I ECpost with spheres indicating the positions of mutations associated with AFDCIN (red), neurodegenerative diseases (black), and TCS (blue). b–f Close-up views of the positions of disease-associated mutations. Mutant residues and potential contacting residues are shown in sticks.
