Fig. 3: Human HF TAC contains heterogeneous populations with distinct lineage tendencies. | Cell Discovery

Fig. 3: Human HF TAC contains heterogeneous populations with distinct lineage tendencies.

From: Single-cell transcriptomics reveals lineage trajectory of human scalp hair follicle and informs mechanisms of hair graying

Fig. 3

a Subclustering of PR cells and marker genes expression visualized on UMAP. b Subclustering UMAP of MxTA cells from a. c Representative marker genes expression visualized on MxTA subclustering UMAP. COMkr: CO markers; IRSMkr: IRS markers; FCMkr: FC markers; MEMkr: ME markers. d Palantir branch probabilities for CO, IRS, FC, and ME cell lineages in Matrix TA cells. Cells were colored according to their Palantir branch probabilities. e UMAP visualization of Matrix TA cells, but with cells now colored according to their monocle3 pseudo-time (left) and diffusion pseudo-time (right), respectively. The root cell was indicated in red. f Diffusion map of the single cells along the top three diffusion components (DC). Cells were colored according to subclusters in b. The root cell was indicated in red and putative lineage trajectories displaying the bifurcation into CO, IRS, FC, and ME lineages were shown in black.

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