Table 1 Nineteen proteins selected by genetic algorithm and previously known associations with thyroid physiology or pathology.
From: Artificial intelligence defines protein-based classification of thyroid nodules
Uniprot ID | Gene name | Protein name | Thyroid cancer related | Thyroid function related |
|---|---|---|---|---|
P04083 | ANXA1 | Annexin A1 | Yes | Yes |
P17931 | LGALS3 | Galectin-3 | Yes | Yes |
P02751 | FN1 | Fibronectin (FN) | Yes | Yes |
P10909 | CLU | Clusterin | Yes | Yes |
P00568 | AK1 | Adenylate kinase isoenzyme 1 (AK1) | Yes | Yes |
P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | Yes | Yes |
P30086 | PEBP1 | Phosphatidylethanolamine-binding protein 1 | Yes | Yes |
P27797 | CALR | Calreticulin | Yes | Yes |
P78527 | PRKDC | DNA-dependent protein kinase catalytic subunit | Yes | Yes |
O00339 | MATN2 | Matrilin-2 | Yes | – |
P02765 | AHSG | Alpha-2-HS-glycoprotein | Yes | – |
P04792 | HSPB1 | Heat shock protein beta-1 | Yes | – |
O75347 | TBCA | Tubulin-specific chaperone A | – | Yes |
P04216 | THY1 | Thy-1 membrane glycoprotein | – | Yes |
Q9HAT2 | SIAE | Sialate O-acetylesterase | – | – |
O14964 | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate | – | – |
P58546 | MTPN | Myotrophin | – | – |
P83731 | RPL24 | 60 S ribosomal protein L24 | – | – |
P57737 | CORO7 | Coronin-7 | – | – |
