Fig. 2: Expression heterogeneity of nonmalignant cells in the SBC ecosystem.

a UMAP plot of each selected canonical marker genes for identifying the clusters. b Fifteen immune cell clusters (marked by numbers) can be partitioned into eight sub-clusters (marked by the text in black) according to the known markers. c Dot plot shows the expression of known marker genes in these eight immune cell sub-clusters. d Comparison of SBC-infiltrated and HCL immune cells in PD-1, PD-L1, PD-L2, and multiple PD-L1 regulators.