Fig. 1: Characteristics and sera neutralization of the Omicron sub-lineages. | Cell Discovery

Fig. 1: Characteristics and sera neutralization of the Omicron sub-lineages.

From: Neutralization of Omicron BA.4/BA.5 and BA.2.75 by booster vaccination or BA.2 breakthrough infection sera

Fig. 1

a Prevalence and spike mutations of the Omicron sub-lineages and Delta variant based on all the sequences available in GISAID since Jan 1st, 2022. Coverage indicates the total percentage of the indicated lineages in GISAID database. b Neutralization of pseudotyped WT (D614G), Delta and Omicron sub-lineage viruses by sera collected from individuals on day 14 after vaccination with a BBIBP-CorV homologous booster or with a ZF001 heterologous booster dose following two doses of BBIBP-CorV, or infection by BA.2 virus after three doses of BBIBP-CorV vaccination. For all panels, values above the symbols denote GMT and the fold-change was calculated by comparing the titer to WT. c In parallel comparison of neutralization titers against distinct SARS-CoV-2 variants by sera collected from individuals on day 14 after vaccination with homologous or heterologous booster, or breakthrough infection with BA.2 virus. P values were determined by multiple Mann-Whitney tests.

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