Fig. 4: RBD-specific T-cell responses against WT SARS-CoV-2 in vitro. | Cell Discovery

Fig. 4: RBD-specific T-cell responses against WT SARS-CoV-2 in vitro.

From: SARS-CoV-2 vaccination-infection pattern imprints and diversifies T cell differentiation and neutralizing response against Omicron subvariants

Fig. 4

a Representative flow cytometry plots in the I-I-δ, I-I-ο, M-M-ο, and I-I-I groups showing RBD-specific CD4+ and CD8+ T-cell responses against WT RBD peptide pool. b, c Frequency and numbers of all RBD-specific CD4+ and CD8+ T cells in the I-I-δ (n = 23), I-I-ο (n = 21), M-M-ο (n = 8), and I-I-I (n = 40) groups. The number in magenta indicates the mean in the frequency and numbers of detected responses. Each dot represents one donor. Comparisons were performed using Mann–Whitney tests. *P < 0.05, **P < 0.01, ***P < 0.001.

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