Fig. 6: Unique regulatory pathways control neutrophil subsets phenotype during BU pathogenesis. | Cell Discovery

Fig. 6: Unique regulatory pathways control neutrophil subsets phenotype during BU pathogenesis.

From: Sex-specific circulating unconventional neutrophils determine immunological outcome of auto-inflammatory Behçet’s uveitis

Fig. 6

a Heatmap showing the mean expression of TFs in each neutrophil subset (cells from BU patients: n = 18; HCs: n = 16). b GO analysis of TFs’ target genes; red: increased target genes; green: decreased target genes. c UMAP plot overlays showing selected TF expression distribution across clusters. d Volcano plot showing the differentially expressed TFs (adjusted P-value < 0.05) in the different cluster subsets between BU patients and HCs. In all instances, n refers to the number of each group.

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