Table 1 The culture conditions of the different mouse embryonic stem cells.

From: The building blocks of embryo models: embryonic and extraembryonic stem cells

  1. Red (−), pathway inhibition. Green (+), pathway activation. Blue, basal medium.
  2. Molecule compounds function: CHIR99021: an inhibitor of the GSK3; XAV939: a tankyrase inhibitor; IWR-1 endo: a tankyrase inhibitor; IWP2: a WNT pathway inhibitor; inhibits Porcupine; PD0325901: a MEK inhibitor; LIF: Leukemia Inhibitory Factor, the activator of the JAK kinase family; BMS493: an inverse agonist for retinoic acid receptors; JNK Inhibitor VIII: a JNKs (which are a group of MAPKs) inhibitor; SB203580: an inhibitor of p38 MAP kinase; SGC0946: a methyltransferase DOT1L inhibitor; A-366: a methyltransferase G9a/GLP inhibitor; AS8351: an inhibitor of KDM5B; MiH: minocycline hydrochloride, a PARP inhibitor; DiM: (S)- (+)-dimethindene maleate, an inhibitor of the histamine and the muscarinic receptors; PlaB: Pladienolide B, a RNA splicing inhibitor.
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