Fig. 1: Domain organization of caspases. | Cell Discovery

Fig. 1: Domain organization of caspases.

From: Caspases: structural and molecular mechanisms and functions in cell death, innate immunity, and disease

Fig. 1

General domain organization, followed by human and mouse caspase classification based on domain organization. Domain boundaries were taken from human caspase UniprotKB annotations. The historic classifications based on canonical function are shown by the highlighting color on the caspase name. CARD caspase activation and recruitment domain, DED death effector domain.

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