Fig. 2: Structural representation of caspase dimer.

Caspase zymogen (PDB ID: 1GQF) with each protomer unit of the caspase heterodimer colored in pink and cornflower blue, respectively. The active site loops L1–L4, intersubunit linker (L2/L2’ and IL), and L1’ from the second heterodimer are shown. Positions of β strands β1–β6 and helices H1–H5 are indicated.