Fig. 3
From: RNA N6-methyladenosine modification in cancers: current status and perspectives
ALKBH5 plays an oncogenic role in brain tumor and breast cancer. a ALKBH5 enhances self-renewal and proliferation of GSCs and promotes tumorigenesis through regulating expression of FOXM1 with the aid of FOXM1-AS. b HIF-induced ALKBH5 expression mediates the upregulation of pluripotency factor expression and the enrichment/specification of BCSCs in the hypoxic environment
